Carl Chartrand-Lefebvre

• Imagerie des artères coronaires chez le patient HIV (angiographie coronarienne non invasive, imagerie de la plaque, graisse épicardique, impact psychologique)
• Imagerie non invasive des pontages coronariens par tomodensitométrie (perméabilité après chirurgie sous et sans circulation extracorporelle, nouveau design chirurgical, analyse morphométrique)
• Imagerie des stents coronariens par tomodensitométrie
• Produits de contraste en angiographie par tomodensitométrie

• Le programme d'imagerie cardiovasculaire en VIH -Obtention d'une subvention des Instituts de recherche en santé du Canada
• Subvention de 2,5 M$ pour étudier les mécanismes du vieillissement avec le VIH
• La plaque coronarienne non calcifiée, plus à risque, est plus fréquente chez les individus vivant avec le VIH
• Essai clinique RESTART: un espoir pour les personnes vivant avec le VIH

Publications choisies

Sadouni M, Duquet-Armand M, Elkeddeh MG, El-Far M, Larouche-Anctil E, Tremblay C, Baril J-G, Benoit Trottier, Chartrand-Lefebvre C, Durand M; for the investigators of the Canadian HIV and Aging Cohort Study. Epicardial fat density, coronary artery disease and inflammation in people living with HIV. Medicine 2023; 102: e32980  

Louis-Mathieu Stevens, Carl Chartrand-Lefebvre, Samer Mansour, Vincent Béland, Gilles Soulez, Jessica Forcillo, Fadi Basile, Ignacio Prieto, Nicolas Noiseux.  Anterolateral territory coronary artery bypass grafting strategies: a prospective non-inferiority randomized clinical trial. Eur J Cardiothorac Surg. 2023;63:ezad060 

Giguère K, Chartrand-Lefebvre C, Baril JG, Conway B, El-Far M, Falutz J, Harris M, Jenabian MA, Leipsic J, Loutfy M, Mansour S, MacPherson P, Margolese S, McMillan JM, Monteith K, Murray MCM, Pick N, Thomas R, Trottier B, Trottier S, Tsoukas C, Walmsley S, Wong A, Tremblay C, Durand M; Canadian HIV And Aging Cohort Study Group. Baseline characteristics of a prospective cohort study of aging and cardiovascular diseases among people living with HIV. HIV Med. 2023; 24:1210-1221

Courchesne M, Manrique G, Bernier L, Moussa L, Cresson J, Gutzeit A, Johannes M. Froehlich JM, Koh D-M, Chartrand-Lefebvre C, Matoori S. Gender Differences in Pharmacokinetics: A Perspective on Contrast Agents. ACS Pharmacol Transl Sci. 2023;7:8-17

Zdanovich E, Naim C, Stevens LM, Mansour S, Semionov A, Juneau D, Chartrand-Lefebvre C.  Coronary bioresorbable stents: non-invasive quantitative evaluation of intra- and juxta-stent plaque composition - A computed tomography longitudinal study. PlosOne 2022; 17: e0268456

Boldeanu I, Sadouni M, Mansour S, Baril J-G, Trottier B, Soulez G, Chin AS, Leipsic J, Tremblay C, Durand M, Chartrand-Lefebvre C; For the investigators of the Canadian HIV and Aging Cohort Study. Prevalence and characterization of subclinical coronary atherosclerotic plaque with CT among individuals with HIV – Results from the Canadian HIV and Aging Cohort Study. Radiology 2021 299:3, 571-580 (Editorial dans la même édition de Radiology)

Sadouni M, Durand M, Boldeanu I, Danielli C, Bodson-Clermont P, Mansour S, Baril JG, Trottier B, Tremblay C, Chartrand-Lefebvre C; For the investigators of the Canadian HIV and Aging Cohort Study.  Association of epicardial fat with non-calcified coronary plaque volume and with low attenuation plaque in people living with HIV. AIDS. 2021; 35:1575-1584

Durand M, Chartrand-Lefebvre C, Baril J-G, Trottier S, Trottier B, Harris M, Walmsley S, Conway B, Wong A, Routy J-P, Kovacs C, MacPherson PA, Monteith KM, Mansour S, Thanassoulis G, Abrahamovicz M, Zhu Z, Tsoukas C, Ancuta P, Bernard N, Tremblay CL. The Canadian HIV and Aging Cohort Study - Determinants of increased risk of cardio-vascular diseases in HIV-infected individuals: rationale and study protocol.  BMC Infectious Diseases (2017) 17:611-621

Noiseux N, Stevens L-M, Chartrand-Lefebvre C, Soulez G, Prieto I, Basile F, Mansour S, Dyub A M, Kieser T M, Lamy A; For the CORONARY investigators.  Off-pump versus on-pump coronary artery bypass surgery - Graft patency assessment with coronary CT angiography. A prospective multicenter randomized controlled pilot study.  J Thorac Imaging. 2017; 32:370-377

C Chartrand-Lefebvre, White CS, Bhalla S, Mayo-Smith WW, Prenovault J, Vydareny KH, Soto J, Ozkan O, Chughtai A, Soulez G. Comparison of the effect of a low-osmolar and an iso-osmolar agent on heart rate during chest CT angiography – Results of a prospective randomized multicenter study. Radiology 2011; 258:930-937